Cargando…
Structure-based assessment of disease-related mutations in human voltage-gated sodium channels
Voltage-gated sodium (Na(v)) channels are essential for the rapid upstroke of action potentials and the propagation of electrical signals in nerves and muscles. Defects of Na(v) channels are associated with a variety of channelopathies. More than 1000 disease-related mutations have been identified i...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Higher Education Press
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445024/ https://www.ncbi.nlm.nih.gov/pubmed/28150151 http://dx.doi.org/10.1007/s13238-017-0372-z |