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Detrimental effect of maternal and post-weaning high-fat diet on the reproductive function in the adult female offspring rat: roles of insulin-like growth factor 2 and the ovarian circadian clock

PURPOSE: We evaluate the impact of maternal and post-weaning high-fat (HF) diet on ovarian follicular population, steroidogenesis, and gene expression with a focus on the circadian clock system and insulin-like growth factor 2 (Igf2) in adult offspring ovaries, and to elucidate whether a maternal an...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Ju, Tsai, Ching-Chou, Huang, Li-Tung, Sheen, Jiunn-Ming, Tiao, Mao-Meng, Yu, Hong-Ren, Chen, Chih-Cheng, Tain, You-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445052/
https://www.ncbi.nlm.nih.gov/pubmed/28417351
http://dx.doi.org/10.1007/s10815-017-0915-5