High throughput resistance profiling of Plasmodium falciparum infections based on custom dual indexing and Illumina next generation sequencing-technology

Genetic polymorphisms in P. falciparum can be used to indicate the parasite’s susceptibility to antimalarial drugs as well as its geographical origin. Both of these factors are key to monitoring development and spread of antimalarial drug resistance. In this study, we combine multiplex PCR, custom d...

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Detalles Bibliográficos
Autores principales: Nag, Sidsel, Dalgaard, Marlene D., Kofoed, Poul-Erik, Ursing, Johan, Crespo, Marina, Andersen, Lee O’Brien, Aarestrup, Frank Møller, Lund, Ole, Alifrangis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445084/
https://www.ncbi.nlm.nih.gov/pubmed/28546554
http://dx.doi.org/10.1038/s41598-017-02724-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445084/
https://www.ncbi.nlm.nih.gov/pubmed/28546554
http://dx.doi.org/10.1038/s41598-017-02724-x

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