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High throughput resistance profiling of Plasmodium falciparum infections based on custom dual indexing and Illumina next generation sequencing-technology
Genetic polymorphisms in P. falciparum can be used to indicate the parasite’s susceptibility to antimalarial drugs as well as its geographical origin. Both of these factors are key to monitoring development and spread of antimalarial drug resistance. In this study, we combine multiplex PCR, custom d...
Autores principales: | Nag, Sidsel, Dalgaard, Marlene D., Kofoed, Poul-Erik, Ursing, Johan, Crespo, Marina, Andersen, Lee O’Brien, Aarestrup, Frank Møller, Lund, Ole, Alifrangis, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445084/ https://www.ncbi.nlm.nih.gov/pubmed/28546554 http://dx.doi.org/10.1038/s41598-017-02724-x |
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