Thymic homing of activated CD4(+) T cells induces degeneration of the thymic epithelium through excessive RANK signaling

Activated T cells have been shown to be able to recirculate into the thymus from the periphery. The present study was aimed to elucidate the functional consequences of thymic homing of activated T cells upon developing thymocytes and thymic epithelial cells (TEC). In the presence of activated T cell...

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Detalles Bibliográficos
Autores principales: Yin, Chen, Pei, Xiao-Yan, Shen, Hui, Gao, Ya-Nan, Sun, Xiu-Yuan, Wang, Wei, Ge, Qing, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445095/
https://www.ncbi.nlm.nih.gov/pubmed/28546567
http://dx.doi.org/10.1038/s41598-017-02653-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445095/
https://www.ncbi.nlm.nih.gov/pubmed/28546567
http://dx.doi.org/10.1038/s41598-017-02653-9

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