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Thymic homing of activated CD4(+) T cells induces degeneration of the thymic epithelium through excessive RANK signaling
Activated T cells have been shown to be able to recirculate into the thymus from the periphery. The present study was aimed to elucidate the functional consequences of thymic homing of activated T cells upon developing thymocytes and thymic epithelial cells (TEC). In the presence of activated T cell...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445095/ https://www.ncbi.nlm.nih.gov/pubmed/28546567 http://dx.doi.org/10.1038/s41598-017-02653-9 |