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KIR3DS1-Mediated Recognition of HLA-*B51: Modulation of KIR3DS1 Responsiveness by Self HLA-B Allotypes and Effect on NK Cell Licensing

Several studies described an association between killer-cell immunoglobulin-like receptor (KIR)/HLA gene combinations and clinical outcomes in various diseases. In particular, an important combined role for KIR3DS1 and HLA-B Bw4-I80 in controlling viral infections and a higher protection against leu...

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Detalles Bibliográficos
Autores principales: Carlomagno, Simona, Falco, Michela, Bono, Maria, Alicata, Claudia, Garbarino, Lucia, Mazzocco, Michela, Moretta, Lorenzo, Moretta, Alessandro, Sivori, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445109/
https://www.ncbi.nlm.nih.gov/pubmed/28603523
http://dx.doi.org/10.3389/fimmu.2017.00581