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Photochemically Controlled Drug Dosing from a Polymeric Scaffold

PURPOSE: To develop the first photoactive biomaterial coating capable of controlled drug dosing via inclusion of synthesised drug-3,5-dimethoxybenzoin (DMB) conjugates in a poly(2-methyoxyethyl acrylate) (pMEA) scaffold. METHODS: Flurbiprofen- and naproxen-DMB conjugates were prepared via esterifica...

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Detalles Bibliográficos
Autores principales: Donnelly, Louise, Hardy, John G., Gorman, Sean P., Jones, David S., Irwin, Nicola J., McCoy, Colin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445155/
https://www.ncbi.nlm.nih.gov/pubmed/28508123
http://dx.doi.org/10.1007/s11095-017-2164-9