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Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: a GENFI study

Frontotemporal dementia is a heterogeneous neurodegenerative disorder with around a third of cases having autosomal dominant inheritance. There is wide variability in phenotype even within affected families, raising questions about the determinants of the progression of disease and age at onset. It...

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Detalles Bibliográficos
Autores principales: Premi, Enrico, Grassi, Mario, van Swieten, John, Galimberti, Daniela, Graff, Caroline, Masellis, Mario, Tartaglia, Carmela, Tagliavini, Fabrizio, Rowe, James B., Laforce Jr, Robert, Finger, Elizabeth, Frisoni, Giovanni B., de Mendonça, Alexandre, Sorbi, Sandro, Gazzina, Stefano, Cosseddu, Maura, Archetti, Silvana, Gasparotti, Roberto, Manes, Marta, Alberici, Antonella, Cardoso, Manuel J., Bocchetta, Martina, Cash, David M., Ourselin, Sebastian, Padovani, Alessandro, Rohrer, Jonathan D., Borroni, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445253/
https://www.ncbi.nlm.nih.gov/pubmed/28460069
http://dx.doi.org/10.1093/brain/awx103