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Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: a GENFI study
Frontotemporal dementia is a heterogeneous neurodegenerative disorder with around a third of cases having autosomal dominant inheritance. There is wide variability in phenotype even within affected families, raising questions about the determinants of the progression of disease and age at onset. It...
Autores principales: | Premi, Enrico, Grassi, Mario, van Swieten, John, Galimberti, Daniela, Graff, Caroline, Masellis, Mario, Tartaglia, Carmela, Tagliavini, Fabrizio, Rowe, James B., Laforce Jr, Robert, Finger, Elizabeth, Frisoni, Giovanni B., de Mendonça, Alexandre, Sorbi, Sandro, Gazzina, Stefano, Cosseddu, Maura, Archetti, Silvana, Gasparotti, Roberto, Manes, Marta, Alberici, Antonella, Cardoso, Manuel J., Bocchetta, Martina, Cash, David M., Ourselin, Sebastian, Padovani, Alessandro, Rohrer, Jonathan D., Borroni, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445253/ https://www.ncbi.nlm.nih.gov/pubmed/28460069 http://dx.doi.org/10.1093/brain/awx103 |
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