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Increased serum level of soluble interleukin-2 receptor is associated with a worse response of metastatic clear cell renal cell carcinoma to interferon alpha and sequential VEGF-targeting therapy

BACKGROUND: Renal cell carcinoma (RCC) is a tumor with immunogenic properties. Soluble interleukin-2 receptor (sIL-2R) has a role in T cell activation and may be important for immune regulation in various conditions, including infections, transplantation rejection, autoimmune inflammatory states, an...

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Detalles Bibliográficos
Autores principales: Nukui, Akinori, Masuda, Akinori, Abe, Hideyuki, Arai, Kyoko, Yoshida, Ken-Ichiro, Kamai, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445282/
https://www.ncbi.nlm.nih.gov/pubmed/28545581
http://dx.doi.org/10.1186/s12885-017-3369-3