Cargando…

Increased serum level of soluble interleukin-2 receptor is associated with a worse response of metastatic clear cell renal cell carcinoma to interferon alpha and sequential VEGF-targeting therapy

BACKGROUND: Renal cell carcinoma (RCC) is a tumor with immunogenic properties. Soluble interleukin-2 receptor (sIL-2R) has a role in T cell activation and may be important for immune regulation in various conditions, including infections, transplantation rejection, autoimmune inflammatory states, an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nukui, Akinori, Masuda, Akinori, Abe, Hideyuki, Arai, Kyoko, Yoshida, Ken-Ichiro, Kamai, Takao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445282/ https://www.ncbi.nlm.nih.gov/pubmed/28545581 http://dx.doi.org/10.1186/s12885-017-3369-3

Ejemplares similares

Higher preoperative serum levels of PD‐L1 and B7‐H4 are associated with invasive and metastatic potential and predictable for poor response to VEGF‐targeted therapy and unfavorable prognosis of renal cell carcinoma
por: Fukuda, Takehiko, et al.
Publicado: (2016)

Germline polymorphism of interferon-lambda3 is clinically associated with progression of renal cell carcinoma
por: Nukui, Akinori, et al.
Publicado: (2017)

Clinical Significance of Serum Soluble T Cell Regulatory Molecules in Clear Cell Renal Cell Carcinoma
por: Masuda, Akinori, et al.
Publicado: (2014)

Increased expression of adenosine 2A receptors in metastatic renal cell carcinoma is associated with poorer response to anti-vascular endothelial growth factor agents and anti-PD-1/Anti-CTLA4 antibodies and shorter survival
por: Kamai, Takao, et al.
Publicado: (2021)

Clinically significant association of elevated expression of nuclear factor E2-related factor 2 expression with higher glucose uptake and progression of upper urinary tract cancer
por: Nukui, Akinori, et al.
Publicado: (2018)

Increased interferon alpha receptor 2 mRNA levels is associated with renal cell carcinoma metastasis
por: Kamai, Takao, et al.
Publicado: (2007)

Association of cancer progression with elevated expression of programmed cell death protein 1 ligand 1 by upper tract urothelial carcinoma and increased tumor-infiltrating lymphocyte density
por: Nukui, Akinori, et al.
Publicado: (2020)

Seasonal Changes in Lower Urinary Tract Symptoms in Japanese Men With Benign Prostatic Hyperplasia Treated With α(1)-Blockers
por: Kobayashi, Minoru, et al.
Publicado: (2017)

Immunohistochemical expressionof sodium-dependent glucose transporter - 2 (SGLT-2) in clear cell renal carcinoma: possible prognostic implications
por: Kobayashi, Minoru, et al.
Publicado: (2019)

Increased expression of system large amino acid transporter (LAT)-1 mRNA is associated with invasive potential and unfavorable prognosis of human clear cell renal cell carcinoma
por: Betsunoh, Hironori, et al.
Publicado: (2013)

Increased serum hepcidin-25 level and increased tumor expression of hepcidin mRNA are associated with metastasis of renal cell carcinoma
por: Kamai, Takao, et al.
Publicado: (2009)

Serum interferon alpha receptor 2 mRNA may predict efficacy of interferon alpha with/without low-dose sorafenib for metastatic clear cell renal cell carcinoma
por: Furuya, Nobutaka, et al.
Publicado: (2011)

Circulating tumor cells and cell-free tumor DNA analyses in urothelial cancer using the LiquidBiopsy platform
por: Kobayashi, Minoru, et al.
Publicado: (2022)

Radical nephrectomy and regional lymph node dissection for locally advanced type 2 papillary renal cell carcinoma in an at-risk individual from a family with hereditary leiomyomatosis and renal cell cancer: a case report
por: Kamai, Takao, et al.
Publicado: (2016)

Successful management of ureteral injury after gender-affirming laparoscopic hysterectomy: A case report
por: Nakamura, Gaku, et al.
Publicado: (2022)

Axitinib for preoperative downstaging of renal cell carcinoma with sarcomatoid differentiation and direct invasion of the duodenum and inferior vena cava: a case report
por: Yuki, Hideo, et al.
Publicado: (2014)

Cancer immunohistogram representing cancer-immunity cycle by immunohistochemistry predicts the efficacy of immune checkpoint inhibitors in urological cancer patients
por: Kijima, Toshiki, et al.
Publicado: (2022)

The Rho-kinase inhibitor HA-1077 suppresses proliferation/migration and induces apoptosis of urothelial cancer cells
por: Abe, Hideyuki, et al.
Publicado: (2014)

Abnormal 18F-FDG uptakes in the prostate due to two different conditions of urine reflux: a mimicker of prostate cancer
por: Inamura, Kensuke, et al.
Publicado: (2016)

Single nucleotide variants of succinate dehydrogenase A gene in renal cell carcinoma
por: Kamai, Takao, et al.
Publicado: (2021)

Performance characteristics of prostate-specific antigen density and biopsy core details to predict oncological outcome in patients with intermediate to high-risk prostate cancer underwent robot-assisted radical prostatectomy
por: Yashi, Masahiro, et al.
Publicado: (2017)

Increased Nrf2 expression by renal cell carcinoma is associated with postoperative chronic kidney disease and an unfavorable prognosis
por: Yuki, Hideo, et al.
Publicado: (2018)

Prostate volume and biopsy tumor length are significant predictors for classical and redefined insignificant cancer on prostatectomy specimens in Japanese men with favorable pathologic features on biopsy
por: Yashi, Masahiro, et al.
Publicado: (2014)

Transperitoneal laparoscopic umbilical resection of urachal remnants: a feasible surgical method
por: Yuki, Hideo, et al.
Publicado: (2023)

Protein Profiling of Blood Samples from Patients with Hereditary Leiomyomatosis and Renal Cell Cancer by Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometry
por: Kamai, Takao, et al.
Publicado: (2012)

Nrf2 gene mutation and single nucleotide polymorphism rs6721961 of the Nrf2 promoter region in renal cell cancer
por: Yamaguchi, Yoshiyuki, et al.
Publicado: (2019)

Increased co-expression of stromal HHLA2 and fibroblast activation protein in upper tract urothelial carcinoma
por: Nishihara, Daisaku, et al.
Publicado: (2023)

Elevated expression of B7 homolog 4 is associated with disease progression in upper urinary tract urothelial carcinoma
por: Mizuno, Tomoya, et al.
Publicado: (2021)

Association of Nrf2 expression and mutation with Weiss and Helsinki scores in adrenocortical carcinoma
por: Kamai, Takao, et al.
Publicado: (2022)

A case of clear cell renal cell carcinoma with vena cava thrombus responding to presurgical avelumab, and axitinib
por: Suzuki, Issei, et al.
Publicado: (2021)

Augmented interferon regulatory factor 7 axis in whole tumor cell vaccines prevents tumor recurrence by inducing interferon gamma-secreting B cells
por: Kajihara, Nabeel, et al.
Publicado: (2023)

Serum soluble interleukin-2 receptor levels for screening for malignant lymphomas and differential diagnosis from other conditions
por: Murakami, Jun, et al.
Publicado: (2019)

Single minimum incision endoscopic radical nephrectomy for renal tumors with preoperative virtual navigation using 3D-CT volume-rendering
por: Kamai, Takao, et al.
Publicado: (2010)

Increased Rac1 activity and Pak1 overexpression are associated with lymphovascular invasion and lymph node metastasis of upper urinary tract cancer
por: Kamai, Takao, et al.
Publicado: (2010)

Decreased CDKL2 Expression in Clear Cell Renal Cell Carcinoma Predicts Worse Overall Survival
por: Chen, Zhan, et al.
Publicado: (2022)

A Case of Metastatic Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome-Associated Renal Cell Carcinoma Treated with a Sequence of Axitinib and Nivolumab Following Cytoreductive Nephrectomy
por: Yonese, Ichiro, et al.
Publicado: (2020)

Low level of Cyclin‐D1 correlates with worse prognosis of clear cell renal cell carcinoma patients
por: Wang, Qing‐shui, et al.
Publicado: (2019)

Increased expression of Nrf2 and elevated glucose uptake in pheochromocytoma and paraganglioma with SDHB gene mutation
por: Kamai, Takao, et al.
Publicado: (2022)

Computational Modeling of Interacting VEGF and Soluble VEGF Receptor Concentration Gradients
por: Hashambhoy, Yasmin L., et al.
Publicado: (2011)

Spontaneous regression of multiple pulmonary metastases accompanied by normalization of serum immune markers following cytoreductive nephrectomy in a patient with clear‐cell renal cell carcinoma
por: Okazaki, Akihito, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_np4bag7jou51b4g7kcca51i33g