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Selection and characterization of alanine racemase inhibitors against Aeromonas hydrophila
BACKGROUND: Combining experimental and computational screening methods has been of keen interest in drug discovery. In the present study, we developed an efficient screening method that has been used to screen 2100 small-molecule compounds for alanine racemase Alr-2 inhibitors. RESULTS: We identifie...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445283/ https://www.ncbi.nlm.nih.gov/pubmed/28545531 http://dx.doi.org/10.1186/s12866-017-1010-x |