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A plea to provide best evidence in trials under sample-size restrictions: the example of pioglitazone to resolve leukoplakia and erythroplakia in Fanconi anemia patients

In planning a clinical trial for demonstrating the efficacy of pioglitazone to resolve leukoplakia and erythroplakia in Fanconi anemia patients we had to discuss the need for a randomized controlled trial particularly under sample-size restrictions as very promising results were available from a sin...

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Detalles Bibliográficos
Autores principales: Lasch, Florian, Weber, Kristina, Chao, Mwe Mwe, Koch, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445360/
https://www.ncbi.nlm.nih.gov/pubmed/28545482
http://dx.doi.org/10.1186/s13023-017-0655-8