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A random effects model for the identification of differential splicing (REIDS) using exon and HTA arrays
BACKGROUND: Alternative gene splicing is a common phenomenon in which a single gene gives rise to multiple transcript isoforms. The process is strictly guided and involves a multitude of proteins and regulatory complexes. Unfortunately, aberrant splicing events do occur which have been linked to gen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445373/ https://www.ncbi.nlm.nih.gov/pubmed/28545391 http://dx.doi.org/10.1186/s12859-017-1687-8 |