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Open-label versus double-blind placebo treatment in irritable bowel syndrome: study protocol for a randomized controlled trial

BACKGROUND: Placebo medications, by definition, are composed of inactive ingredients that have no physiological effect on symptoms. Nonetheless, administration of placebo in randomized controlled trials (RCTs) and in clinical settings has been demonstrated to have significant impact on many physical...

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Bibliographic Details
Main Authors: Ballou, Sarah, Kaptchuk, Ted J., Hirsch, William, Nee, Judy, Iturrino, Johanna, Hall, Kathryn T., Kelley, John M., Cheng, Vivian, Kirsch, Irving, Jacobson, Eric, Conboy, Lisa, Lembo, Anthony, Davis, Roger B.
Format: Online Article Text
Language:English
Published: BioMed Central 2017
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445390/
https://www.ncbi.nlm.nih.gov/pubmed/28545508
http://dx.doi.org/10.1186/s13063-017-1964-x