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BRD4 inhibition suppresses cell growth, migration and invasion of salivary adenoid cystic carcinoma

BACKGROUND: Bromodomain-containing protein 4 (BRD4) inhibition is a new therapeutic strategy for many malignancies. In this study, we aimed to explore the effect of BRD4 inhibition by JQ1 on in vitro cell growth, migration and invasion of salivary adenoid cystic carcinoma (SACC). METHODS: The human...

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Detalles Bibliográficos
Autores principales: Wang, Limei, Wu, Xiuyin, Wang, Ruolin, Yang, Chengzhe, Li, Zhi, Wang, Cunwei, Zhang, Fenghe, Yang, Pishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445403/
https://www.ncbi.nlm.nih.gov/pubmed/28545522
http://dx.doi.org/10.1186/s40659-017-0124-9