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Endoplasmic reticulum stress and inflammation in the central nervous system

Persistent endoplasmic reticulum (ER) stress is thought to drive the pathology of many chronic disorders due to its potential to elicit aberrant inflammatory signaling and facilitate cell death. In neurodegenerative diseases, the accumulation of misfolded proteins and concomitant induction of ER str...

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Detalles Bibliográficos
Autores principales: Sprenkle, Neil T., Sims, Savannah G., Sánchez, Cristina L., Meares, Gordon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445486/
https://www.ncbi.nlm.nih.gov/pubmed/28545479
http://dx.doi.org/10.1186/s13024-017-0183-y