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MAL gene overexpression as a marker of high-grade serous ovarian carcinoma stem-like cells that predicts chemoresistance and poor prognosis

BACKGROUND: The existence of cancer stem cells (CSCs) within a tumor bulk has been demonstrated for many solid tumors including epithelial ovarian carcinoma (EOC). CSCs have been associated to tumor invasion, metastasis and development of chemoresistant recurrences. In this context, we aim to charac...

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Detalles Bibliográficos
Autores principales: Zanotti, Laura, Romani, Chiara, Tassone, Laura, Todeschini, Paola, Tassi, Renata Alessandra, Bandiera, Elisabetta, Damia, Giovanna, Ricci, Francesca, Ardighieri, Laura, Calza, Stefano, Marchini, Sergio, Beltrame, Luca, Tognon, Germana, D’Incalci, Maurizio, Pecorelli, Sergio, Sartori, Enrico, Odicino, Franco, Ravaggi, Antonella, Bignotti, Eliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445497/
https://www.ncbi.nlm.nih.gov/pubmed/28545541
http://dx.doi.org/10.1186/s12885-017-3334-1