PSE-HMM: genome-wide CNV detection from NGS data using an HMM with Position-Specific Emission probabilities

BACKGROUND: Copy Number Variation (CNV) is envisaged to be a major source of large structural variations in the human genome. In recent years, many studies apply Next Generation Sequencing (NGS) data for the CNV detection. However, still there is a necessity to invent more accurate computational too...

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Detalles Bibliográficos
Autores principales: Malekpour, Seyed Amir, Pezeshk, Hamid, Sadeghi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445519/
https://www.ncbi.nlm.nih.gov/pubmed/27809781
http://dx.doi.org/10.1186/s12859-016-1296-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445519/
https://www.ncbi.nlm.nih.gov/pubmed/27809781
http://dx.doi.org/10.1186/s12859-016-1296-y

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