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PSE-HMM: genome-wide CNV detection from NGS data using an HMM with Position-Specific Emission probabilities
BACKGROUND: Copy Number Variation (CNV) is envisaged to be a major source of large structural variations in the human genome. In recent years, many studies apply Next Generation Sequencing (NGS) data for the CNV detection. However, still there is a necessity to invent more accurate computational too...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445519/ https://www.ncbi.nlm.nih.gov/pubmed/27809781 http://dx.doi.org/10.1186/s12859-016-1296-y |