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Compaction of Duplex Nucleic Acids upon Native Electrospray Mass Spectrometry

[Image: see text] We report on the fate of nucleic acids conformation in the gas phase as sampled using native mass spectrometry coupled to ion mobility spectrometry. On the basis of several successful reports for proteins and their complexes, the technique has become popular in structural biology,...

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Detalles Bibliográficos
Autores principales: Porrini, Massimiliano, Rosu, Frédéric, Rabin, Clémence, Darré, Leonardo, Gómez, Hansel, Orozco, Modesto, Gabelica, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445532/
https://www.ncbi.nlm.nih.gov/pubmed/28573208
http://dx.doi.org/10.1021/acscentsci.7b00084