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Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span

Mechanisms that ensure and maintain the stability of genetic information are fundamentally important for organismal function and can have a large impact on disease, aging, and life span. While a multi-layered cellular apparatus exists to detect and respond to DNA damage, various insults from environ...

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Detalles Bibliográficos
Autores principales: Garschall, Kathrin, Dellago, Hanna, Gáliková, Martina, Schosserer, Markus, Flatt, Thomas, Grillari, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445577/
https://www.ncbi.nlm.nih.gov/pubmed/28649423
http://dx.doi.org/10.1038/s41514-017-0005-z