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Both overlapping and independent mechanisms determine how diet and insulin-ligand knockouts extend lifespan of Drosophila melanogaster

Lifespan in many organisms, including Drosophila melanogaster, can be increased by reduced insulin-IGF-like signaling (IIS) or by changes in diet. Most studies testing whether IIS is involved in diet-mediated lifespan extension employ only a few diets, but recent data shows that a broad range of nut...

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Detalles Bibliográficos
Autores principales: Zandveld, Jelle, van den Heuvel, Joost, Zwaan, Bastiaan J., Piper, Matthew D.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445580/
https://www.ncbi.nlm.nih.gov/pubmed/28649422
http://dx.doi.org/10.1038/s41514-017-0004-0