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On the performance of de novo pathway enrichment

De novo pathway enrichment is a powerful approach to discover previously uncharacterized molecular mechanisms in addition to already known pathways. To achieve this, condition-specific functional modules are extracted from large interaction networks. Here, we give an overview of the state of the art...

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Detalles Bibliográficos
Autores principales: Batra, Richa, Alcaraz, Nicolas, Gitzhofer, Kevin, Pauling, Josch, Ditzel, Henrik J., Hellmuth, Marc, Baumbach, Jan, List, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445589/
https://www.ncbi.nlm.nih.gov/pubmed/28649433
http://dx.doi.org/10.1038/s41540-017-0007-2