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Role of the p53/p21 system in the response of human colon carcinoma cells to Doxorubicin

BACKGROUND: Colon adenocarcinomas are refractory to a number of widely used anticancer agents. Multifactorial mechanisms have been implicated in this intrinsically resistant phenotype, including deregulation of cell death pathways. In this regard, the p53 protein has a well established role in the c...

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Detalles Bibliográficos
Autores principales: Ravizza, Raffaella, Gariboldi, Marzia B, Passarelli, Laura, Monti, Elena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544559/
https://www.ncbi.nlm.nih.gov/pubmed/15601469
http://dx.doi.org/10.1186/1471-2407-4-92