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Role of the p53/p21 system in the response of human colon carcinoma cells to Doxorubicin
BACKGROUND: Colon adenocarcinomas are refractory to a number of widely used anticancer agents. Multifactorial mechanisms have been implicated in this intrinsically resistant phenotype, including deregulation of cell death pathways. In this regard, the p53 protein has a well established role in the c...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544559/ https://www.ncbi.nlm.nih.gov/pubmed/15601469 http://dx.doi.org/10.1186/1471-2407-4-92 |