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Molecular stratification of early breast cancer identifies drug targets to drive stratified medicine

Many women with hormone receptor-positive early breast cancer can be managed effectively with endocrine therapies alone. However, additional systemic chemotherapy treatment is necessary for others. The clinical challenges in managing high-risk women are to identify existing and novel druggable targe...

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Detalles Bibliográficos
Autores principales: Bayani, Jane, Yao, Cindy Q., Quintayo, Mary Anne, Yan, Fu, Haider, Syed, D’Costa, Alister, Brookes, Cassandra L., van de Velde, Cornelis J. H., Hasenburg, Annette, Kieback, Dirk G., Markopoulos, Christos, Dirix, Luc, Seynaeve, Caroline, Rea, Daniel, Boutros, Paul C., Bartlett, John M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445616/
https://www.ncbi.nlm.nih.gov/pubmed/28649643
http://dx.doi.org/10.1038/s41523-016-0003-5