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Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells

Dry eye disease is the most prevalent pathological condition in aging eyes. One potential therapeutic strategy is the transplantation of lacrimal glands, generated in vitro from pluripotent stem cells such as human embryonic stem cells, into patients. One of the preceding requirements is a method to...

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Detalles Bibliográficos
Autores principales: Hirayama, Masatoshi, Ko, Shigeru B.H., Kawakita, Tetsuya, Akiyama, Tomohiko, Goparaju, Sravan K., Soma, Atsumi, Nakatake, Yuhki, Sakota, Miki, Chikazawa-Nohtomi, Nana, Shimmura, Shigeto, Tsubota, Kazuo, Ko, Minoru S.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445629/
https://www.ncbi.nlm.nih.gov/pubmed/28649419
http://dx.doi.org/10.1038/s41514-016-0001-8