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Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells
Dry eye disease is the most prevalent pathological condition in aging eyes. One potential therapeutic strategy is the transplantation of lacrimal glands, generated in vitro from pluripotent stem cells such as human embryonic stem cells, into patients. One of the preceding requirements is a method to...
Autores principales: | Hirayama, Masatoshi, Ko, Shigeru B.H., Kawakita, Tetsuya, Akiyama, Tomohiko, Goparaju, Sravan K., Soma, Atsumi, Nakatake, Yuhki, Sakota, Miki, Chikazawa-Nohtomi, Nana, Shimmura, Shigeto, Tsubota, Kazuo, Ko, Minoru S.H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445629/ https://www.ncbi.nlm.nih.gov/pubmed/28649419 http://dx.doi.org/10.1038/s41514-016-0001-8 |
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