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A functional hierarchical organization of the protein sequence space
BACKGROUND: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patterns in known proteins based on manually-validated alignments of known protein families. Such methods can achieve high sen...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544566/ https://www.ncbi.nlm.nih.gov/pubmed/15596019 http://dx.doi.org/10.1186/1471-2105-5-196 |