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A functional hierarchical organization of the protein sequence space

BACKGROUND: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patterns in known proteins based on manually-validated alignments of known protein families. Such methods can achieve high sen...

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Detalles Bibliográficos
Autores principales: Kaplan, Noam, Friedlich, Moriah, Fromer, Menachem, Linial, Michal
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544566/
https://www.ncbi.nlm.nih.gov/pubmed/15596019
http://dx.doi.org/10.1186/1471-2105-5-196