Retroviral transduction of peptide stimulated t cells can generate dual t cell receptor-expressing (bifunctional) t cells reactive with two defined antigens

BACKGROUND: Tumors and viruses have developed many mechanisms to evade the immune system, including down-regulation of target antigens and MHC molecules. These immune escape mechanisms may be able to be circumvented by adoptively transferring T cells engineered to express two different T cell recept...

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Detalles Bibliográficos
Autores principales: Langerman, Alexander, Callender, Glenda G, Nishimura, Michael I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544585/
https://www.ncbi.nlm.nih.gov/pubmed/15588290
http://dx.doi.org/10.1186/1479-5876-2-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544585/
https://www.ncbi.nlm.nih.gov/pubmed/15588290
http://dx.doi.org/10.1186/1479-5876-2-42

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