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Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes

BACKGROUND: Evolutionarily conserved sequences within or adjoining orthologous genes often serve as critical cis-regulatory regions. Recent studies have identified long, non-coding genomic regions that are perfectly conserved between human and mouse, termed ultra-conserved regions (UCRs). Here, we f...

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Detalles Bibliográficos
Autores principales: Sandelin, Albin, Bailey, Peter, Bruce, Sara, Engström, Pär G, Klos, Joanna M, Wasserman, Wyeth W, Ericson, Johan, Lenhard, Boris
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544600/
https://www.ncbi.nlm.nih.gov/pubmed/15613238
http://dx.doi.org/10.1186/1471-2164-5-99