In vivo imaging of clock gene expression in multiple tissues of freely moving mice

Clock genes are expressed throughout the body, although how they oscillate in unrestrained animals is not known. Here, we show an in vivo imaging technique that enables long-term simultaneous imaging of multiple tissues. We use dual-focal 3D tracking and signal-intensity calibration to follow gene e...

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Detalles Bibliográficos
Autores principales: Hamada, Toshiyuki, Sutherland, Kenneth, Ishikawa, Masayori, Miyamoto, Naoki, Honma, Sato, Shirato, Hiroki, Honma, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446038/
https://www.ncbi.nlm.nih.gov/pubmed/27285820
http://dx.doi.org/10.1038/ncomms11705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446038/
https://www.ncbi.nlm.nih.gov/pubmed/27285820
http://dx.doi.org/10.1038/ncomms11705

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