SPHK1 (sphingosine kinase 1) induces epithelial-mesenchymal transition by promoting the autophagy-linked lysosomal degradation of CDH1/E-cadherin in hepatoma cells

SPHK1 (sphingosine kinase 1), a regulator of sphingolipid metabolites, plays a causal role in the development of hepatocellular carcinoma (HCC) through augmenting HCC invasion and metastasis. However, the mechanism by which SPHK1 signaling promotes invasion and metastasis in HCC remains to be clarif...

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Detalles Bibliográficos
Autores principales: Liu, Hong, Ma, Yan, He, Hong-Wei, Zhao, Wu-Li, Shao, Rong-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446059/
https://www.ncbi.nlm.nih.gov/pubmed/28521610
http://dx.doi.org/10.1080/15548627.2017.1291479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446059/
https://www.ncbi.nlm.nih.gov/pubmed/28521610
http://dx.doi.org/10.1080/15548627.2017.1291479

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