Pharmacological modulators of autophagy activate a parallel noncanonical pathway driving unconventional LC3 lipidation

The modulation of canonical macroautophagy/autophagy for therapeutic benefit is an emerging strategy of medical and pharmaceutical interest. Many drugs act to inhibit autophagic flux by targeting lysosome function, while others were developed to activate the pathway. Here, we report the surprising f...

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Detalles Bibliográficos
Autores principales: Jacquin, Elise, Leclerc-Mercier, Stéphanie, Judon, Celine, Blanchard, Emmanuelle, Fraitag, Sylvie, Florey, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446083/
https://www.ncbi.nlm.nih.gov/pubmed/28296541
http://dx.doi.org/10.1080/15548627.2017.1287653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446083/
https://www.ncbi.nlm.nih.gov/pubmed/28296541
http://dx.doi.org/10.1080/15548627.2017.1287653

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