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Sequence statistics of tertiary structural motifs reflect protein stability

The Protein Data Bank (PDB) has been a key resource for learning general rules of sequence-structure relationships in proteins. Quantitative insights have been gained by defining geometric descriptors of structure (e.g., distances, dihedral angles, solvent exposure, etc.) and observing their distrib...

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Detalles Bibliográficos
Autores principales: Zheng, Fan, Grigoryan, Gevorg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446159/
https://www.ncbi.nlm.nih.gov/pubmed/28552940
http://dx.doi.org/10.1371/journal.pone.0178272