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CCL20 secreted from IgA1-stimulated human mesangial cells recruits inflammatory Th17 cells in IgA nephropathy

IgA nephropathy (IgAN) is the most common primary glomerulonephritis characterized by human mesangial cells (HMC) proliferation and extracellular matrix expansion associated with immune deposits consisting of galactose-deficient IgA1. However, how IgA1 contributes to IgAN has yet to be completely el...

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Detalles Bibliográficos
Autores principales: Lu, Guoyuan, Zhang, Xiaopan, Shen, Lei, Qiao, Qing, Li, Yuan, Sun, Jieqiong, Zhang, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446182/
https://www.ncbi.nlm.nih.gov/pubmed/28552941
http://dx.doi.org/10.1371/journal.pone.0178352