Conservation and innovation in the DUX4-family gene network

Facioscapulohumeral dystrophy (FSHD; OMIM #158900, #158901) is caused by mis-expression of the DUX4 transcription factor in skeletal muscle(1). Animal models of FSHD are hampered by incomplete knowledge of the conservation of the DUX4 transcriptional program in other species(2–5). Despite divergence...

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Detalles Bibliográficos
Autores principales: Whiddon, Jennifer L., Langford, Ashlee T., Wong, Chao-Jen, Zhong, Jun Wen, Tapscott, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446306/
https://www.ncbi.nlm.nih.gov/pubmed/28459454
http://dx.doi.org/10.1038/ng.3846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446306/
https://www.ncbi.nlm.nih.gov/pubmed/28459454
http://dx.doi.org/10.1038/ng.3846

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