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Conservation and innovation in the DUX4-family gene network
Facioscapulohumeral dystrophy (FSHD; OMIM #158900, #158901) is caused by mis-expression of the DUX4 transcription factor in skeletal muscle(1). Animal models of FSHD are hampered by incomplete knowledge of the conservation of the DUX4 transcriptional program in other species(2–5). Despite divergence...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446306/ https://www.ncbi.nlm.nih.gov/pubmed/28459454 http://dx.doi.org/10.1038/ng.3846 |