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High-resolution bioelectrical imaging of Aβ-induced network dysfunction on CMOS-MEAs for neurotoxicity and rescue studies

Neurotoxicity and the accumulation of extracellular amyloid-beta(1–42) (Aβ) peptides are associated with the development of Alzheimer’s disease (AD) and correlate with neuronal activity and network dysfunctions, ultimately leading to cellular death. However, research on neurodegenerative diseases is...

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Detalles Bibliográficos
Autores principales: Amin, Hayder, Nieus, Thierry, Lonardoni, Davide, Maccione, Alessandro, Berdondini, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446416/
https://www.ncbi.nlm.nih.gov/pubmed/28550283
http://dx.doi.org/10.1038/s41598-017-02635-x