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Anti-proliferative Effects of Nucleotides on Gastric Cancer via a Novel P2Y6/SOCE/Ca(2+)/β-catenin Pathway

Although purinegic signaling is important in regulating gastric physiological functions, it is currently unknown for its role in gastric cancer (GC). We demonstrate for the first time that the expression of P2Y6 receptors was markedly down-regulated in human GC cells and primary GC tissues compared...

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Detalles Bibliográficos
Autores principales: Wan, Hanxing, Xie, Rui, Xu, Jiangyu, He, Jialin, Tang, Bo, Liu, Qingqing, Wang, Sumin, Guo, Yanjun, Yang, Xin, Dong, Tobias Xiao, Carethers, John M., Yang, Shiming, Dong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446419/
https://www.ncbi.nlm.nih.gov/pubmed/28550303
http://dx.doi.org/10.1038/s41598-017-02562-x