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Anti-proliferative Effects of Nucleotides on Gastric Cancer via a Novel P2Y6/SOCE/Ca(2+)/β-catenin Pathway
Although purinegic signaling is important in regulating gastric physiological functions, it is currently unknown for its role in gastric cancer (GC). We demonstrate for the first time that the expression of P2Y6 receptors was markedly down-regulated in human GC cells and primary GC tissues compared...
Autores principales: | Wan, Hanxing, Xie, Rui, Xu, Jiangyu, He, Jialin, Tang, Bo, Liu, Qingqing, Wang, Sumin, Guo, Yanjun, Yang, Xin, Dong, Tobias Xiao, Carethers, John M., Yang, Shiming, Dong, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446419/ https://www.ncbi.nlm.nih.gov/pubmed/28550303 http://dx.doi.org/10.1038/s41598-017-02562-x |
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