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EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS

BACKGROUND: Cell-cycle disruption is the major characteristic features of neoplastic transformation and the status of cell-cycle regulators can thus be utilized to assess the prognostic significance in patients with cancer. The PCNA, cyclin D1, CDK4, CDK6 and survivin expression in the buccal mucosa...

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Detalles Bibliográficos
Autores principales: Manimaran, Asokan, Buddhan, Rajamanickam, Manoharan, Shanmugam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: African Traditional Herbal Medicine Supporters Initiative (ATHMSI) 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446469/
https://www.ncbi.nlm.nih.gov/pubmed/28573225
http://dx.doi.org/10.21010/ajtcam.v14i2.10