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Tetherin Inhibits Cell-Free Virus Dissemination and Retards Murine Leukemia Virus Pathogenesis

The relative contributions of cell-free virion circulation and direct cell-to-cell transmission to retroviral dissemination and pathogenesis are unknown. Tetherin/Bst2 is an antiviral protein that blocks enveloped virion release into the extracellular milieu but may not inhibit cell-to-cell virus tr...

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Detalles Bibliográficos
Autores principales: Liberatore, Rachel A., Mastrocola, Emily J., Powell, Chelsea, Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446635/
https://www.ncbi.nlm.nih.gov/pubmed/28381565
http://dx.doi.org/10.1128/JVI.02286-16