Cargando…

Tetherin Inhibits Cell-Free Virus Dissemination and Retards Murine Leukemia Virus Pathogenesis

The relative contributions of cell-free virion circulation and direct cell-to-cell transmission to retroviral dissemination and pathogenesis are unknown. Tetherin/Bst2 is an antiviral protein that blocks enveloped virion release into the extracellular milieu but may not inhibit cell-to-cell virus tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liberatore, Rachel A., Mastrocola, Emily J., Powell, Chelsea, Bieniasz, Paul D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446635/ https://www.ncbi.nlm.nih.gov/pubmed/28381565 http://dx.doi.org/10.1128/JVI.02286-16

Ejemplares similares

Lymphatic Dissemination of Simian Immunodeficiency Virus after Penile Inoculation
por: Ma, Zhong-Min, et al.
Publicado: (2016)

Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes
por: Umviligihozo, Gisele, et al.
Publicado: (2020)

Interleukin-27 Promotes Divergent Effects on HIV-1 Infection in Peripheral Blood Mononuclear Cells through BST-2/Tetherin
por: Temerozo, Jairo R., et al.
Publicado: (2023)

Tick Saliva Enhances Powassan Virus Transmission to the Host, Influencing Its Dissemination and the Course of Disease
por: Hermance, Meghan E., et al.
Publicado: (2015)

Herpes Simplex Virus 1 Targets the Murine Olfactory Neuroepithelium for Host Entry
por: Shivkumar, Maitreyi, et al.
Publicado: (2013)

Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus
por: Deng, Xufang, et al.
Publicado: (2020)

TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection
por: Iwata-Yoshikawa, Naoko, et al.
Publicado: (2019)

Prior Heterologous Flavivirus Exposure Results in Reduced Pathogenesis in a Mouse Model of Zika Virus Infection
por: Hassert, Mariah, et al.
Publicado: (2021)

Levels of Influenza A Virus Defective Viral Genomes Determine Pathogenesis in the BALB/c Mouse Model
por: Penn, Rebecca, et al.
Publicado: (2022)

Characterization of a Unique Novel LORF3 Protein of Duck Plague Virus and Its Potential Pathogenesis
por: Shen, Bingjie, et al.
Publicado: (2023)

IRF5 Promotes Influenza Virus-Induced Inflammatory Responses in Human Induced Pluripotent Stem Cell-Derived Myeloid Cells and Murine Models
por: Forbester, Jessica L., et al.
Publicado: (2020)

Virus and Host Factors Affecting the Clinical Outcome of Bluetongue Virus Infection
por: Caporale, Marco, et al.
Publicado: (2014)

Establishment of a Cynomolgus Macaque Model of Human T-Cell Leukemia Virus Type 1 (HTLV-1) Infection by Direct Inoculation of Adult T-Cell Leukemia Patient-Derived Cell Lines for HTLV-1 Infection
por: Urano, Emiko, et al.
Publicado: (2022)

Identification of Embryonic Chicken Proteases Activating Newcastle Disease Virus and Their Roles in the Pathogenicity of Virus Used as In Ovo Vaccine
por: Feng, Helong, et al.
Publicado: (2023)

Epstein-Barr Virus-Specific CD8 T Cells Selectively Infiltrate the Brain in Multiple Sclerosis and Interact Locally with Virus-Infected Cells: Clue for a Virus-Driven Immunopathological Mechanism
por: Serafini, Barbara, et al.
Publicado: (2019)

Deletion of the African Swine Fever Virus Gene DP148R Does Not Reduce Virus Replication in Culture but Reduces Virus Virulence in Pigs and Induces High Levels of Protection against Challenge
por: Reis, Ana L., et al.
Publicado: (2017)

Seminal Simian Immunodeficiency Virus in Chronically Infected Cynomolgus Macaques Is Dominated by Virus Originating from Multiple Genital Organs
por: Houzet, Laurent, et al.
Publicado: (2018)

Mouse Saliva Inhibits Transit of Influenza Virus to the Lower Respiratory Tract by Efficiently Blocking Influenza Virus Neuraminidase Activity
por: Gilbertson, Brad, et al.
Publicado: (2017)

Activation of AIM2 by hepatitis B virus results in antiviral immunity that suppresses hepatitis C virus during coinfection
por: Li, Yongqi, et al.
Publicado: (2023)

Asymptomatic Primary Infection with Epstein-Barr Virus: Observations on Young Adult Cases
por: Abbott, Rachel J., et al.
Publicado: (2017)

Mutation of Influenza A Virus PA-X Decreases Pathogenicity in Chicken Embryos and Can Increase the Yield of Reassortant Candidate Vaccine Viruses
por: Hussain, Saira, et al.
Publicado: (2019)

SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1
por: Brown, James R., et al.
Publicado: (2016)

Evaluation of the Interactions between Mumps Virus and Guinea Pig
por: Lang Balija, Maja, et al.
Publicado: (2023)

Assessing the Protective Potential of H1N1 Influenza Virus Hemagglutinin Head and Stalk Antibodies in Humans
por: Christensen, Shannon R., et al.
Publicado: (2019)

Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background
por: Shin, Dai-Lun, et al.
Publicado: (2015)

The Acquisition and Retention of Lumpy Skin Disease Virus by Blood-Feeding Insects Is Influenced by the Source of Virus, the Insect Body Part, and the Time since Feeding
por: Sanz-Bernardo, Beatriz, et al.
Publicado: (2022)

African-Lineage Zika Virus Replication Dynamics and Maternal-Fetal Interface Infection in Pregnant Rhesus Macaques
por: Crooks, Chelsea M., et al.
Publicado: (2021)

Porcine Hemagglutinating Encephalomyelitis Virus Infection In Vivo and Ex Vivo
por: Mora-Díaz, Juan Carlos, et al.
Publicado: (2021)

Characterization of Ebola Virus Mucosal Challenge Routes in Cynomolgus Macaques
por: Johnson, Dylan M., et al.
Publicado: (2023)

Multiple Genome Segments Determine Virulence of Bluetongue Virus Serotype 8
por: Janowicz, Anna, et al.
Publicado: (2015)

Expanding Regulatory T Cells Alleviates Chikungunya Virus-Induced Pathology in Mice
por: Lee, Wendy W. L., et al.
Publicado: (2015)

Chicken and Duck Myotubes Are Highly Susceptible and Permissive to Influenza Virus Infection
por: Baquero-Perez, Belinda, et al.
Publicado: (2014)

Naturally Occurring Single Mutations in Ebola Virus Observably Impact Infectivity
por: Wong, Gary, et al.
Publicado: (2018)

Avatar Mice Underscore the Role of the T Cell-Dendritic Cell Crosstalk in Ebola Virus Disease and Reveal Mechanisms of Protection in Survivors
por: Rottstegge, Monika, et al.
Publicado: (2022)

Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines
por: Celma, Cristina C., et al.
Publicado: (2016)

Targeting of the Nasal Mucosa by Japanese Encephalitis Virus for Non-Vector-Borne Transmission
por: García-Nicolás, Obdulio, et al.
Publicado: (2018)

Mechanisms of Abrupt Loss of Virus Control in a Cohort of Previous HIV Controllers
por: Rosás-Umbert, Miriam, et al.
Publicado: (2019)

NK Cells Accumulate in Infected Tissues and Contribute to Pathogenicity of Ebola Virus in Mice
por: Fausther-Bovendo, H., et al.
Publicado: (2019)

Infectious Herpes Simplex Virus in the Brain Stem Is Correlated with Reactivation in the Trigeminal Ganglia
por: Doll, Jessica R., et al.
Publicado: (2019)

Genetic Determinants of Altered Virulence of Type O Foot-and-Mouth Disease Virus
por: Yang, Fan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_36i99jfk5pnieplpe1vh1oa82i