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Expression of von Hippel–Lindau tumor suppressor protein (pVHL) characteristic of tongue cancer and proliferative lesions in tongue epithelium

BACKGROUND: Patients with tongue cancer frequently show loss of heterozygosity (LOH) of the von Hippel–Lindau (VHL) tumor suppressor gene. However, expression of VHL protein (pVHL) in tongue cancer has rarely been investigated and remains largely unknown. We performed immunohistochemical staining of...

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Detalles Bibliográficos
Autores principales: Hasegawa, Hisashi, Kusumi, Yoshiaki, Asakawa, Takeshi, Maeda, Miyoko, Oinuma, Toshinori, Furusaka, Tohru, Oshima, Takeshi, Esumi, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446680/
https://www.ncbi.nlm.nih.gov/pubmed/28549422
http://dx.doi.org/10.1186/s12885-017-3364-8