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Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinoma

BACKGROUND: Glyoxalase 1 is a key enzyme in the detoxification of reactive metabolites such as methylglyoxal and induced Glyoxalase 1 expression has been demonstrated for several human malignancies. However, the regulation and clinical relevance of Glyoxalase 1 in the context of head and neck squamo...

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Detalles Bibliográficos
Autores principales: Kreycy, Nele, Gotzian, Christiane, Fleming, Thomas, Flechtenmacher, Christa, Grabe, Niels, Plinkert, Peter, Hess, Jochen, Zaoui, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446730/
https://www.ncbi.nlm.nih.gov/pubmed/28549423
http://dx.doi.org/10.1186/s12885-017-3367-5