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Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects

Braak and Del Tredici have proposed that typical Parkinson disease (PD) has its origins in the olfactory bulb and gastrointestinal tract. However, the role of the olfactory system has insufficiently been explored in the pathogeneses of PD and Alzheimer disease (AD) in laboratory models. Here, we dem...

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Detalles Bibliográficos
Autores principales: Tomlinson, Julianna J., Shutinoski, Bojan, Dong, Li, Meng, Fanyi, Elleithy, Dina, Lengacher, Nathalie A., Nguyen, Angela P., Cron, Greg O., Jiang, Qiubo, Roberson, Erik D., Nussbaum, Robert L., Majbour, Nour K., El-Agnaf, Omar M., Bennett, Steffany A., Lagace, Diane C., Woulfe, John M., Sad, Subash, Brown, Earl G., Schlossmacher, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446848/
https://www.ncbi.nlm.nih.gov/pubmed/28477284
http://dx.doi.org/10.1007/s00702-017-1726-7