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Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects
Braak and Del Tredici have proposed that typical Parkinson disease (PD) has its origins in the olfactory bulb and gastrointestinal tract. However, the role of the olfactory system has insufficiently been explored in the pathogeneses of PD and Alzheimer disease (AD) in laboratory models. Here, we dem...
Autores principales: | Tomlinson, Julianna J., Shutinoski, Bojan, Dong, Li, Meng, Fanyi, Elleithy, Dina, Lengacher, Nathalie A., Nguyen, Angela P., Cron, Greg O., Jiang, Qiubo, Roberson, Erik D., Nussbaum, Robert L., Majbour, Nour K., El-Agnaf, Omar M., Bennett, Steffany A., Lagace, Diane C., Woulfe, John M., Sad, Subash, Brown, Earl G., Schlossmacher, Michael G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446848/ https://www.ncbi.nlm.nih.gov/pubmed/28477284 http://dx.doi.org/10.1007/s00702-017-1726-7 |
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